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Early loss of HIV-infected patients on potent antiretroviral therapy programmes in lower-income countries

Martin WG Brinkhof, François Dabis, Landon Myer, David R Bangsberg, Andrew Boulle, Denis Nash, Mauro Schechter, Christian Laurent, Olivia Keiser, Margaret May, Eduardo Sprinz, Matthias Egger, Xavier Anglaret, for the ART-LINC of IeDEA collaboration

Volume 86, Number 7, July 2008, 559-567

Table 2. Baseline characteristics of the 5491 patients starting ART who were included in the data analysis

Characteristics Number of patients
(n) (%)
Age (years)
16–29 1312 24
30–39 2491 45
40–49 1232 23
≥ 50 456 8
Median 35 30–41a
Sex
Female 2519 46
Male 2972 54
Baseline CD4-cell count (cells/µl)
≤ 25 810 20b
25–49 482 12b
50–99 680 17b
100–199 1001 24b
200–349 767 19b
≥ 350 347 8b
Median 105 35–210a
Not measured 1404 26
Clinical stage
CDC stage A/B, WHO stage I/II 760 14
CDC stage C, WHO stage III/IV 1727 31
Not recorded 3004 55
Initial ART regimen
NNRTI-based 4031 73
PI-based 988 18
Unknown or other combination 472 9
Year of starting ART
≤ 2000 1463 27
2001–2002 2432 44
2003–2004 1596 29

ART, antiretroviral therapy; CDC, Centers for Disease Control and Prevention; NNRTI, non-nucleoside reverse transcriptase inhibitor; PI, protease inhibitor.a Value is the interquartile range.b Percentage of the 4087 patients whose CD4-cell count was available.