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Marburg haemorrhagic fever
Photo essay: Managing Marburg fever in Uganda
Photo essay: Controlling the Marburg outbreak in Angola
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Disease Outbreak News: Marburg
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Marburg haemorrhagic fever - fact sheet (French) (Spanish) (Portuguese)
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Images from the outbreak of Marburg haemorrhagic fever in Uige Province, Angola 2005
Marburg haemorrhagic fever is a severe and highly fatal disease caused by a virus from the same family as the one that causes Ebola haemorrhagic fever. These viruses are among the most virulent pathogens known to infect humans. Both diseases are rare, but have a capacity to cause dramatic outbreaks with high fatality.
Illness caused by Marburg virus begins abruptly, with severe headache and severe malaise. Many patients develop severe haemorrhagic manifestations between days 5 and 7, and fatal cases usually have some form of bleeding, often from multiple sites. The disease has no vaccine and no specific treatment. Case fatality rates have varied greatly, from 25% in the initial laboratory-associated outbreak in 1967, to more than 80% in the Democratic Republic of Congo from 1998-2000, to even higher in the outbreak that began in Angola in late 2004.
For more information
Infection control for viral haemorrhagic fevers in the African health care setting
Archives
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Risk Factors for Marburg Hemorrhagic Fever, Democratic Republic of the Congo Emerging Infectious Diseases Journal.Volume 9, Number 12, December 2003
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Viral haemorrhagic fever/Marburg, Democratic Republic of the Congo Weekly Epidemiological Record. 21 May 1999, Vol 74, 20
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Viral haemorrhagic fevers. Report of a WHO Expert Committee (pages 78-88)
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Surveillance of Ebola/Marburg fevers
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Viral haemorrhagic fevers of man. Bulletin of the World Health Organization, 56 (6): 819-832 (1978)
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Marburg and Ebola virus infections: a guide for their diagnosis, management, and control
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